Author
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Mariett, an Anglo-Hungarian, holds a BSc (Hons) in Functional Medicine and Nutritional Therapy. She is a four-time bestselling author, medical astrologer, and holistic medical guide.
Every day, countless people leave medical appointments with a familiar, frustrating phrase by doctors: “Everything looks normal.” And yet—fatigue lingers. Digestion remains unpredictable. Neurological symptoms flare without clear cause. Pain appears where no injury exists. Something is clearly out of balance, but standard tests don’t catch it. The system has no name for it, no treatment plan, and no roadmap forward.
Here, I want to explore an investigative approach to understanding how functional and somatic medicine are helping people move from vague symptoms to real solutions. When we identify patterns, uncover root causes, and support the body’s interconnected systems, these approaches offer clarity and a structured path toward healing.

What Is a “Mysterious Illness”?
If you’ve been told “it’s all in your head,” or have gone from doctor to doctor without answers, know this: your symptoms are valid. Your experience is real. And there are tools and approaches that can help.
Many of these conditions don’t show up on routine lab work. They may affect multiple systems—nervous, immune, digestive, hormonal—so symptoms can seem scattered or “unrelated.”
They also often affect women at much higher rates, and women are more likely to be misdiagnosed, underdiagnosed, or told their symptoms are psychological. Hormonal fluctuations, trauma history, immune sensitivity, and a higher likelihood of being dismissed by providers all contribute to this gender gap.
These symptoms are not imaginary—they just fall outside the limits of current testing.
Common examples include:
- Chronic fatigue that doesn’t improve with rest
- Brain fog, memory issues, or dizziness
- Pain with no clear injury (such as fibromyalgia)
- Digestive symptoms like bloating, nausea, or IBS that don’t respond to treatment
- Heart palpitations, lightheadedness, or blood pressure swings (like POTS)
- Chemical or food sensitivities that worsen over time
- Strange skin sensations, itching, tingling, or rashes with no clear cause
- “Crash” cycles—where small stressors cause major flares in symptoms
Real Conditions Often Called “Mysterious”
Here are some of the most common (and commonly misunderstood) diagnoses that fall under the umbrella of mysterious illness:
- Fibromyalgia
- Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS)
- Postural Orthostatic Tachycardia Syndrome (POTS)
- Mast Cell Activation Syndrome (MCAS)
- Long COVID (PASC)
- Small Fibre Neuropathy
- Functional Neurological Disorder (FND)
- Multiple Chemical Sensitivity (MCS)
- Histamine Intolerance
- Chronic Lyme disease or Post-Treatment Lyme Syndrome (PTLDS)
- Mould illness or Chronic Inflammatory Response Syndrome (CIRS)
- Adrenal dysfunction / burnout / HPA axis dysregulation
- Undiagnosed thyroid issues or hormone imbalances
- Non-celiac gluten sensitivity
- SIBO (Small Intestinal Bacterial Overgrowth)

The Conventional Medicine Gap
For many patients with chronic or mysterious illness, this is where conventional medicine reaches its limits. Not because your symptoms aren’t real, but because the tools being used simply aren’t designed to detect what’s actually going on under the surface.
Conventional medicine is excellent at diagnosing acute disease: infections, organ damage, tumours, fractures, and emergencies. But when it comes to chronic, complex, or systemic dysfunction, its tools often fall short.
Here’s why:
- “Normal range” doesn’t mean optimal. Lab ranges are based on population averages, not what’s ideal for your body. You can be “within range” and still feel exhausted, inflamed, or hormonally imbalanced.
- Standard labs look for disease, not dysfunction. You may have subtle issues in your thyroid, gut, mitochondria, or immune system that don’t qualify as a formal diagnosis—but still disrupt your daily life.
- Imaging can’t detect cellular or biochemical imbalances. MRIs, CT scans, and X-rays won’t pick up things like inflammation at the molecular level, low neurotransmitter function or microbiome disturbances.
- Autoimmune markers may not show until late stages. Some autoimmune diseases present with vague symptoms for years before antibodies or tissue damage appear on labs.
- Stealth infections, toxic exposures, and nervous system dysregulation aren’t routinely screened. Yet these are common drivers of mystery illness.
The 15-Minute Appointment Dilemma
Another challenge lies in the structure of the healthcare system itself.
Most conventional doctors operate on a 15-minute visit model, which leaves little room to explore your full health history, multiple body systems, emotional stress, or environmental exposures.
This means:
- There’s no time to connect the dots between symptoms.
- Your case may be reduced to a single complaint, rather than a pattern of imbalances.
- You’re often referred from one specialist to another—each focusing on a different organ system, without a unified view.
- If your labs are “normal,” your symptoms may be dismissed as anxiety or stress—rather than investigated more deeply.
For patients with complex, systemic illness, this creates a frustrating cycle: short visits, inconclusive results, and no long-term plan.
You Deserve More Than Dismissal
Just because a test doesn’t show it, doesn’t mean it’s not happening. Just because a doctor doesn’t understand it, doesn’t mean it’s not real.
There is a growing world of medicine that does look deeper. It examines your body as an interconnected system, listens to your story, and helps you uncover the why behind your symptoms. This is where functional, somatic and astro medicine step in. This is where healing begins.

Healing Illness Through the Nervous System, Functional Medicine & Soul Mapping
What Actually Helps?
Over the years, we’ve seen that many chronic health issues aren’t just about inflammation or autoimmunity.
They’re often rooted in nervous system dysregulation.
That means the body’s stress-response system—the one that governs rest, digestion, healing, immune response, and hormone balance—is stuck in survival mode.
I look for clues that offer insight into:
- Where your nervous system is naturally more sensitive or reactive
- Where unresolved trauma may be stored in the body
- How your system tends to express stress or inflammation physically
- Your hormonal patterns and cycles
- Whether your immune system leans toward autoimmunity, hypersensitivity, or dysregulation
- Functional Medicine
We use advanced lab testing, gut and immune health analysis, and individualized protocols to find the root causes—whether it’s inflammation, infections, hormone imbalances, or toxic overload.
- Nervous System & Somatic Healing
We gently work with the body’s stress patterns to help it feel safe again. This may include:
- Vagus nerve support
- Breathwork and body-based therapy
- Tools to shift out of “fight, flight, or freeze”
- Practices that restore resilience and connection
- Soul Mapping & Life Context
This is our AstroMedicine approach that goes deeper than standard care. We take into account not just your physical symptoms, but your life story, your emotional history, personality, past traumas, and even your sense of identity and purpose.
The Mystery Is a Message
Mysterious illness isn’t just a medical puzzle. It is a call to listen deeply, to explore the layers beneath your symptoms, and to reclaim your healing story. Functional and somatic medicine aren’t quick fixes. However, they are powerful maps back to wholeness. And in the space between symptoms and diagnosis, something miraculous can happen:
You finally begin to know yourself.